Math on objects
Andrew Hussie, author of the online webcomic Homestuck, stated that he uses computer science as a "source of raw material for absurd kinds of exploitation". The more I learned in my degree and my engineering career, the more I understood early Homestuck. I think one quality of a "Homestuck-like" is a story where you compile all the weird knowledge you've accumulated and turn it into lore for characters to muddle through. Writers tend to gravitate toward what they know, but Hussie did it blatantly, on-purpose, and with such flagrant mockery that what he knew of computer science was either not enough or too boring for him to continue with into the later chapters of the comic. After all, it's a story, not a textbook.
This left a great opportunity for me to pick up the baton.